Ji, Minbiao; Arbel, Michal; Zhang, Lili; Freudiger, Christian W.; Hou, Steven S.; Lin, Dongdong; Yang, Xinju; Bacskai, Brian J.; Xie, X. Sunney "Label-free imaging of amyloid plaques in Alzheimer’s disease with stimulated Raman scattering microscopy," Sci Adv 4(11), eaat7715. DOI:10.1126/sciadv.aat7715 (2018)

Yang, Wenlong; Li, Ang; Suo, Yuanzhen; Lu Fa-Ke; Xie, X. Sunney "Simultaneous two-color stimulated Raman scattering microscopy by adding a fiber amplifier to a 2 ps OPO-based SRS microscope," Opt Lett 42(3), 523-526. DOI:10.1364/OL.42.000523 (2017)

Fu, Dan; Yang, Wenlong; Xie, X. Sunney "Label-free Imaging of Neurotransmitter Acetylcholine at Neuromuscular Junctions with Stimulated Raman Scattering," J Am Chem Soc 139(2), 583−586. DOI:10.1021/jacs.6b10727 (2017)

Tian, Feng; Yang Wenlong; Mordes, Daniel A; Wang, Jin-Yuan; Salameh, Johnny S; Mok, Joanie; Chew, Jeannie; Sharma, Aarti; Leno-Duran, Ester; Suzuki-Uematsu, Satomi; Suzuki, Naoki; Han, Steve S; Lu, Fa-Ke; Ji, Minbiao; Zhang, Rosanna; Liu, Yue; Strominger, Jack; Shneider, Neil A; Petrucelli, Leonard; Xie, X Sunney; Eggan, Kevin "Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging," Nat Commun 7:13283. DOI: 10.1038/ncomms13283 (2016)

Lu, Fa-Ke; Calligaris, David; Olubiyi, Olutayo I.; Norton, Isaiah; Yang, Wenlong; Santagata, Sandro; Xie, X. Sunney; Golby, Alexandra J.; Agar, Nathalie Y. R. "Label-Free Neurosurgical Pathology with Stimulated Raman Imaging," Cancer Res 76, 3451-3462. DOI: 10.1158/0008-5472.CAN-16-027 (2016)

Cheng, Ji-Xin; Xie, X Sunney "Vibrational spectroscopic imaging of living systems: An emerging platform for biology and medicine," Science 350, aaa8870, DOI:10.1126/science.aaa8870 (2015)

Ji, Minbiao; Lewis, Spencer; Camelo-Piragua, Sandra; Ramkissoon, Shakti H; Snuderl, Matija; Venneti, Sriram; Fisher-Hubbard, Amanda; Garrard, Mia; Fu, Dan; Wang, Anthony C; Heth, Jason A; Maher, Cormac O; Sanai, Nader; Johnson, Timothy D; Freudiger, Christian W; Sagher, Oren; Xie, X Sunney and Orringer, Daniel A "Detection of human brain tumor infiltration with quantitative stimulated Raman scattering microscopy," Sci Transl Med 7(309), 309ra163, DOI:10.1126/scitranslmed.aab0195 (2015)

Lu, Fa-Ke; Basu, Srinjan; Igras, Vivien; Hoang, Mai P; Ji, Minbiao; Fu, Dan; Holtom, Gary R; Neel, Victor A; Freudiger, Christian W; Fisher, David E and Xie, X Sunney "Label-free DNA imaging in vivo with stimulated Raman scattering microscopy," Proc Natl Acad Sci USA 112(37), 11624–11629, DOI:10.1073/pnas.1515121112 (2015)

Fu, Dan; Xie, X. Sunney. "Reliable Cell Segmentation Based on Spectral Phasor Analysis of Hyperspectral Stimulated Raman Scattering Imaging Data," Anal. Chem. 9, 4115-4119 DOI:10.1021/ac500014b (2014)

Fu, Dan; Yu, Yong; Folick, Andrew; Currie, Erin; Farese, Robert V., Jr.; Tsai, Tsung-Huang; Xie, X. Sunney; Wang, Meng C. "In Vivo Metabolic Fingerprinting of Neutral Lipids with Hyperspectral Stimulated Raman Scattering Microscopy," J. Am. Chem. Soc. 136, 8820-8828 DOI:10.1021/ja504199s (2014)

Fu, Dan; Zhou, Jing; Zhu, Wenjing Suzanne; Manley, Paul W.; Wang, Y. Karen; Hood, Tami; Wylie, Andrew; Xie, X. Sunney. "Imaging the Intracellular Distribution of Tyrosine Kinase Inhibitors in Living Cells with Quantitative Hyperspectral Stimulated Raman Scattering," Nat Chem 6, 614-622 DOI:10.1038/nchem.1961 (2014)

Freudiger, Christian W.; Yang, Wenlong; Holtom, Gary R.; Peyghambarian, Nasser; Xie, X. Sunney; Kieu, Khanh Q. "Stimulated Raman scattering microscopy with a robust fibre laser source," Nature Photonics 8, 153-159 DOI:10.1038/nphoton.2013.360 (2014)

Ji, Minbiao; Orringer, Daniel A.; Freudiger, Christian W.; Ramkissoon, Shakti; Liu, Xiaohui; Lau, Darryl; Golby, Alexandra J.; Norton, Isaiah; Hayashi, Marika; Agar, Nathalie Y. R.; Young, Geoffrey S.; Spino, Cathie; Santagata, Sandro; Camelo-Piragua, Sandra; Ligon, Keith L.; Sagher, Oren; Xie, X. Sunney. "Rapid, Label-Free Detection of Brain Tumors with Stimulated Raman Scattering Microscopy," Science Translational Medicine 5, 201ra119 DOI: 10.1126/scitranslmed.3005954 (2013)

Fu, Dan; Holtom, Gary; Freudiger, Christian; Zhang, Xu; Xie, X. Sunney. "Hyperspectral Imaging with Stimulated Raman Scattering by Chirped Femtosecond Lasers," J Phys Chem B DOI:10.1021/jp308938t (2013)

Kong, Lingjie; Ji, Minbiao; Holtom, Gary R.; Fu, Dan; Freudiger, Christian W.; Xie, X. Sunney. "Multicolor Stimulated Raman Scattering Microscopy with a Rapidly Tunable Optical Parametric Oscillator," Optics Letters 38, 145-147 (2013).

Freudiger, Christian W.; Pfannl, Rolf; Orringer, Daniel A.; Saar, Brian G.; Ji, Minbiao; Zeng, Qing; Ottoboni, Linda; Ying, Wei; Waeber, Christian; Sims, John R.; De Jager, Philip L.; Sagher, Oren; Philbert, Martin A.; Xu, Xiaoyin; Kesari, Santosh; Xie, X. Sunney; Young, Geoffrey S. "Multicolored stain-free histopathology with coherent Raman imaging," Lab Invest 92, 1492-1502 (2012).

Lu, Fa-Ke; Ji, Minbiao; Fu, Dan; Ni, Xiaohui; Freudiger, Christian W.; Holtom, Gary; Xie, X. Sunney. "Multicolor stimulated Raman scattering microscopy," Mol. Phys. 110, 1927-1932 (2012).

Lefrancois, Simon; Fu, Dan; Holtom, Gary; Kong, Lingjie; Wadsworth, William; Schneider, Patrick; Herda, Robert; Zach, Armin; Xie, X. Sunney; Wise, Frank. Fiber Four-wave Mixing Source for Coherent Anti-Stokes Raman Scattering Microscopy," Optics Letters 37, 1652-1654 (2012).

Zhang, Xu; Roeffaers, Maarten B. J.; Basu, Srinjan; Daniele, Joseph R.; Fu, Dan; Freudiger, Christian; Holtom, Gary; Xie, X. Sunney. Label-Free Live-Cell Imaging of Nucleic Acids Using Stimulated Raman Scattering Microscopy," ChemPhysChem 13, 1054-1059 (2012).

Fu, Dan; Lu, Fa-Ke; Zhang, Xu; Freudiger, Christian; Pernik, Douglas R.; Holtom, Gary; Xie, X. Sunney. Quantitative Chemical Imaging with Multiplex Stimulated Raman Scattering Microscopy," J. Am. Chem. Soc. 134, 3623-3226 (2012).

Saar, Brian G.; Johnston, Richard S.; Freudiger, Christian W.; Xie, X. Sunney; Seibel, Eric J. "Coherent Raman Scattering Fiber Endoscopy," Opt Lett 36, 2396-2398 (2011).

Saar, Brian G.; Contreras-Rojas, L. Rodrigo; Xie, X. Sunney; Guy, Richard H. "Imaging Drug Delivery to Skin with Stimulated Raman Scattering Microscopy," Mol Pharm 8, 969-975 (2011).

Freudiger, Christian W.; Roeffaers, Maarten B. J.; Zhang, Xu; Saar, Brian G.; Min, Wei; Xie, X. Sunney "Optical Heterodyne-Detected Raman-Induced Kerr Effect (OHD-RIKE) Microscopy" J Phys Chem B, 115, 5574-5581 (2011).

Min, Wei; Freudiger, Christian W.; Lu, Sijia ; Xie, X. Sunney "Coherent nonlinear optical imaging: beyond fluorescence microscopy" Annu Rev Phys Chem 62, 507-530 (2011).

Roeffaers, Maarten B. J.; Zhang, Xu; Freudiger, Christian W.; Saar, Brian G.; van Ruijven, Marjolein; van Dalen, Gerard; Xiao, Chunhong; Xie, X. Sunney "Label-free imaging of biomolecules in food products using stimulated Raman microscopy" J Biomed Opt 16(2), 021118-(1-6) (Feb 2011).

Freudiger, Christian W.; Min, Wei; Holtom, Gary R.; Xu, Bingwei; Dantus, Marcos; Xie, X. Sunney "Highly specific label-free molecular imaging with spectrally tailored excitation-stimulated Raman scattering (STE-SRS) microscopy" Nature Photon 5, 103-109 (2011).

Wang, Meng C.; Min, Wei; Freudiger, Christian W.; Ruvkun, Gary; Xie, X. Sunney "RNAi screening for fat regulatory genes with SRS microscopy" Nat Methods 8, 135-138 (2011).

Saar, Brian G.; Freudiger, Christian W.; Reichman, Jay; Stanley, C. Michael; Holtom, Gary R.; Xie, X. Sunney "Video-Rate Molecular Imaging in Vivo with Stimulated Raman Scattering" Science 330, 1368-1370 (2010). (Supplementary Materials)

Chong, Shasha; Min, Wei; Xie, X. Sunney "Ground-State Depletion Microscopy: Detection Sensitivity of Single-Molecule Optical Absorption at Room Temperature" J. Phys. Chem. Lett. 1, 3316-3322 (2010).

Wang, Ke; Freudiger, Christian W.; Lee, Jennifer H.; Saar, Brian G.; Xie, X. Sunney Xie; Xu, Chris "Synchronized time-lens source for coherent Raman scattering microscopy" Optics Express, 18 (2010).

Saar, Brian G.; Zeng, Yining; Freudiger, Christian W.; Liu, Yu-San; Himmel, Michael E.; Xie, X. Sunney; Ding, Shi-You "Label-Free, Real-Time Monitoring of Biomass Processing with Stimulated Raman Scattering Microscopy" Angew. Chem. Int. Ed. 49, 5476-5479 (2010).

Zeng, Yining; Saar, Brian G.; Friedrich, Marcel G.; Chen, Fang; Liu, Yu-San; Dixon, Richard A.; Himmel, Michael E.; Xie, X. Sunney; Ding, Shi-You "Imaging Lignin-Downregulated Alfalfa Using Coherent Anti-Stokes Raman Scattering Microscopy" Bioenerg. Res. (2010)

Kieu, Khanh; Saar, Brian G.; Holtom, Gary R.; Xie, X. Sunney; Wise, Frank W. "High-power picosecond fiber source for coherent Raman microscopy" Optics Letters, 34, 2051-2053 (2009).

Min, Wei; Lu, Sijia; Rueckel, Markus; Holtom,Gary R.; Xie, X. Sunney "Near-Degenerate Four-Wave-Mixing Microscopy" Nano Letters, 9, 2423-2426 (2009).

Saar, Brian G.; Holtom, Gary R.; Freudiger, Christian W.; Ackermann, Chrisita; Hill, Winfield; Xie, X. Sunney "Intracavity wavelength modulation of an optical parametric oscillator for coherent Raman microscopy" Optics Express, 17, 12532-12539 (2009).

Murugkar, S.; Evans, C.L.; Xie, X.S.; Anis, H. "Chemically specific imaging of cryptosporidium oocysts using coherent anti-Stokes Raman scattering (CARS) microscopy" Journal of Microscopy, 233, 244-250 (2009).

Min, Wei; Lu, Sijia; Holtom, Gary R.; Xie, X. Sunney "Triple-Resonance Coherent Anti-Stokes Raman Scattering Microspectroscopy" ChemPhysChem, 10, 344-347 (2009).

Freudiger, Christian W.; Min, Wei; Saar, Brian G.; Lu, Sijia; Holtom, Gary R.; He, Chengwei, Tsai, Jason C.; Kang, Jing X.; Xie, X. Sunney "Label-Free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy" Science, 322, 1857-1861 (2008).

Evans, Conor L.; Xie, X. Sunney "Coherent Anti-Stokes Raman Scattering Microscopy: Chemically Selective Imaging for Biology and Medicine" Annu. Rev. Anal. Chem. 1, 883-909 (2008).

Potma, Eric O.; Xie, X. Sunney "Theory of Spontaneous and Coherent Raman Scattering" in Handbook of Biomedical Nonlinear Optical Microscopy, edited by Barry R. Masters and Peter T.C. So, p 164-186, Oxford University Press, New York, New York (2008).

Potma, Eric O.; Xie, X. Sunney "Coherent Anti-Stokes Raman Scattering (CARS) Microscopy: Instrumentation and Applications" in Handbook of Biomedical Nonlinear Optical Microscopy, edited by Barry R. Masters and Peter T. C. So, p 164-186, Oxford University Press, New York, New York (2008).

Wright, A.J.; Poland, S.P.; Girkin, J.M.; Freudiger, C.W.; Evans, C.L.; Xie, X.S. "Adaptive Optics for enhanced signal in CARS microscopy" Optics Express, 15, 18209-18219 (2007).

Saar, Brian G.; Park, Heung-Shik; Xie, X. Sunney; Lavrentovich, Oleg D. "Three-dimensional imaging of chemical bond orientation in liquid crystals by coherent anti-Stokes Raman scattering microscopy" Optics Express, 15, 13585-13596 (2007).

Evans, Conor L.; Xu, Xiaoyin; Kesari, Santosh; Xie, X. Sunney; Wong, Stephen T.C.; Young, Geoffrey S. "Chemically-selective Imaging of Brain Structures with CARS Microscopy" Optics Express, 15, 12076-12087 (2007).

Nan, Xiaolin; Tonary, Angela M.; Stolow, Albert; Xie, X. Sunney; Pezacki, John P. "Intracellular Imaging of HCV RNA and Cellular Lipids by Using Simultaneous Two-Photon Fluorescence and Coherent Anti-Stokes Raman Scattering Microscopies" ChemBioChem, 7, 1895-1897 (2006).

Xie, X. Sunney; Cheng, Ji-Xin; Potma, Eric O. "Coherent Anti-Stokes Raman Scattering Microscopy" in Handbook of Biological Confocal Microscopy 3rd ed. Edited by James Pawley, p 595-606, Springer Science, New York, 2006

Nan, Xiaolin; Potma, Eric O.; Xie, X. Sunney "Nonperturbative Chemical Imaging of Organelle Transport in Living Cells with Coherent anti-Stokes Raman Scattering Microscopy" Biophys. J., 91, 728-725(2006).

Ganikhanov, Feruz; Evans, Conor L.; Saar, Brian G.; Xie, X. Sunney "High-sensitivity vibrational imaging with frequency modulation coherent anti-Stokes Raman scattering (FM CARS) microscopy" Optics Lett., 31, 1872-1874 (2006).

Légaré, François; Evans, Conor L.; Ganikhanov, Feruz; Xie, X. Sunney "Towards CARS Endoscopy" Opt. Express, 14, 4427-4432 (2006).

Ganikhanov, Feruz; Carrasco, Silvia; Xie, X. Sunney; Katz, Mordechai; Seitz, Wolfgang; Kopf, Daniel "Broadly tunable dual-wavelength light source for coherent anti-Stokes Raman scattering microscopy" Optics Lett., 31, 1292-1294 (2006).

Rakic, Bojana; Noestheden, Matthew; Belanger, Sylvie; Nan, Xiaolin; Evans, Conor L.; Xie, X. Sunney; Pezacki, John Paul "Peroxisome Proliferator-Activated Receptor Alpha Antagonism Inhibits Hepatitis C Virus Replication Source" Chemistry and Biology, 13, 1-8 (2006).

Potma, Eric O.; Evans, Conor L.; Xie, X. Sunney "Heterodyne coherent anti-Stokes Raman scattering (CARS) imaging" Optics Lett., 31, 241 (2006).

Evans, Conor L.; Potma, Eric O.; Puoris'haag, Mehron; Côté, Daniel; Lin, Charles P.; Xie, X. Sunney "Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy" Proc. Natl. Aca. Sci. 102, 16807 (2005).

Potma, Eric O.; Xie, X. Sunney "Direct Visualization of Lipid Phase Segregation in Single Lipid Bilayers with Coherent Anti-Stokes Raman Scattering Microscopy" ChemPhysChem 6, 77 (2005).

Evans, Conor L.; Potma, Eric O.; Xie, X. Sunney "Coherent anti-Stokes Raman scattering interferometry: determination of the real and imaginary components of nonlinear susceptibility ? (3) for vibrational microscopy" Optics Lett. 29, 2923 (2004).

Potma, Eric O. and Xie, X. Sunney "Cars Microscopy for Biology and Medicine" Optics & Photonics News 15, 40 (Nov 2004).

Nan, Xiaolin, Yang, Wei Yuan and Xie, Sunney "CARS Microscopy: Lights Up Lipids in Living Cells" Biophotonics International 11, 44 (2004).

Potma, E. O.; Xie, X. S.; Muntean, L.; Preusser, J.; Jone, D.; Ye, J.; Leone, S. R.; Hinsberg, W. D.; and Schade, W. "Chemical imaging of photoresists with coherent anti-Stokes Raman scattering (CARS) microscopy" J. Phys. Chem. B 108, 1296 (2004).

Cheng, J.-X.; Xie, X. S. "Coherent anti-Stokes Raman scattering microscopy: instrumentation, theory and applications" J. Phys. Chem. B 108, 827 (2004).

Nan, X.; Cheng, J.-X.; Xie, X. S. "Vibrational imaging of lipid droplets in live fibroblast cells with coherent anti-Stokes Raman scattering microscope" J. Lipid Res. 44, 2202 (2003).

Potma, E.; Xie, X. S. "Detection of single lipid bilayers with coherent anti-Stokes Raman scattering (CARS) microscopy" J. Raman Spectrosc. 34, 642 (2003).

Potma, E.; Evans, C.; Xie, X. S.; Jones, R. J.; Ye, J. "Picosecond-pulse amplification with an external passive optical cavity" Optics Lett. 28 1835 (2003).

Cheng, J.-X.; Pautot, S.; Weitz, A. D.; Xie, X. S. "Ordering of Water Molecules Between Phospholipid Bilayers Visualized by Coherent anti-Stokes Raman Scattering Microscopy" PNAS 100, 9826 (2003).

Cheng, J.-X.; Volkmer, A.; Book, L. D.; Xie, X. S. "Multiplex coherent anti-Stokes Raman scattering microspectroscopy and study of lipid vesicles" J. Phys. Chem. B 106, 8493 (2002).

Cheng, J.-X.; Potma, E. O.; Xie, X. S. "Coherent anti-Stokes Raman scattering correlation spectroscopy: probing dynamical processes with chemical selectivity" J. Phys. Chem. A 106, 8561 (2002).

Jones, D.J.; Potma, E. O.; Cheng, J.-X.; Burfeindt, B.; Pang, Y.; Ye, J.; Xie. X. S. "Synchronization of two-passively modelocked, picosecond lasers within 20 fs for coherent anti-Stokes Raman scattering microscopy" Rev. Sci. Instrum. 73, 2843 (2002).

Cheng, J.-X.; Xie, X. S. "Green's function formulation of third-harmonic generation microscopy" JOSA B 19, 1604 (2002).

Potma, E.O.; Jones, D. J.; Cheng, J.-X.; Xie, X. S.; Ye, J. "High sensitivity coherent anti-Stokes Raman scattering microscopy with two tightly synchronized picosecond lasers" Opt. Lett. 27, 1168 (2002).

Cheng, J.-X.; Jia, Y. K., Zheng, G.; Xie. X. S. "Laser scanning coherent anti-Stokes Raman scattering microscopy and applications to cell biology" Biophys. J. 83, 502 (2002).

Cheng, J.-X.; Volkmer, A.; Xie, X. S. "Theoretical and experimental characterization of coherent anti-Stokes Raman scattering microscopy" JOSA B 19, 1363 (2002).

Volkmer, A.; Book, L. D.; Xie, X. S. "Time-resolved coherent anti-Stokes Raman scattering: imaging based on Raman free induction decay" Appl. Phys. Lett. 80, 1505 (2002).

Cheng, J.-X.; Book, L. D.; Xie, X.S. "Polarization coherent anti-Stokes Raman scattering microscopy" Opt. Lett. 26, 1341 (2001).

Volkmer, A.; Cheng, J.-X.; Xie, X. S. "Vibrational imaging with high sensitivity via epidetected coherent anti Stokes Raman scattering microscopy" Phys. Rev. Lett. 87, 23901 (2001).

Cheng, J-X.; Volkmer, A.; Book, L. D.; Xie, X. S. "An epi-detected anti-Stokes Raman scattering (E-CARS) microscope with high spectral resolution and high sensitivity" J. Phys. Chem. B 105, 1277 (2001).

Zumbusch, Andreas; Holtom, Gary R.; Xie, X. Sunney "Vibrational Microscopy Using Coherent Anti-Stokes Raman Scattering," Phys. Rev. Lett. 82, 4142 (1999).